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Pharma

CPhI worldwide 2015

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October 13 - 15, 2015 Madrid/Spain

Solubility



Bioavailability

 

Do you have a poorly soluble drug with insufficient bioavailability?

 

Our solution: Prepare a "solid dispersion" with AQOAT.

 

The active ingredient and the carrier polymer are co-dissolved in a suitable organic solvent. This solution is dried or spray-dried. The resulting amorphous composition shows a significantly greater solubility in aqueous media compared to the original crystalline drug, due to the demolished crystal structure of the active compound.

 

 

Emulsifiying

 

Are you searching for an innovative emulsifier to stabilize your biphasic preparation?

 

Our solution:

 

Metolose / methyl cellulose / water-soluble cellulose ether

 

Ryoto Sugar Ester / nonionic surfactant covering a broad range of HLB-values